How can we decide if any particular measurement near zero is
actually zero or represents a true positive count? There must be some level above which we can be confident, to a degree,
that a net count is valid. This is the critical limit, LC.
If we have a count, A, then when
A >
ka s0,
the count is statistically significant
and when
A £
ka s0,
the count is not significant, where s0
is the standard deviation of the distribution and the factor ka
is selected so as to provide a predetermined degree of confidence
in the solution.
When ka corresponds to the
95% confidence level
where s is the standard deviance of
background estimate (counts).
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Definition of critical limit, LC.
(The vertical axis represents the frequency of observing a particular
count) |